We are working on updates and if any question, please reach at (844) 348-6296
(844) 348-6296

16192 Coastal Highway Lewes, DE 19958

Follow us on Social media

eClaim solution simplifies your health care revenue cycle solutions.

Follow us


eClaim Solution > RCM  > How to Use Medical Billing Modifiers 59, 25, and 91?
Comparison of medical billing modifiers 59, 25, and 91 - ensuring accurate coding and reimbursement in healthcare practices

How to Use Medical Billing Modifiers 59, 25, and 91?

Clear communication is vital for accurate medical billing and seamless insurance reimbursement. Modifiers serve as clarifiers that bridge the gap between complex patient care and billing codes. Among the most commonly used are 59, 25, and 91 – but each has a specific purpose.

Navigating the Modifier Landscape

Modifiers act as translators, bridging the gap between physician services and insurance companies. They provide granular details, ensuring that the nuances of medical care are accurately conveyed. This clarity leads to correct reimbursement and streamlined financial processes.

Modifier 59: Distinct Procedural Services

Modifier 59 signifies that multiple procedures were performed during a single session, but each service stands independently. It highlights that these procedures are not overlapping and deserve separate reimbursement.

When to Use Modifier 59:

  • When the same physician or qualified healthcare professional performs multiple distinct procedures on the same day.

When Not to Use Modifier 59:

  • When the subsequent procedure is part of the global surgical package for the initial procedure.

Modifier 25: Separate E&M Services

Modifier 25 is employed when a patient receives a significant, separately identifiable evaluation and management (E&M) service on the same day as another procedure or service. It emphasizes that the E&M service was distinct and warrants separate reimbursement.

When to Use Modifier 25:

  • When a physician provides a substantial E&M service beyond the primary procedure.

When Not to Use Modifier 25:

  • When the E&M service is part of a global surgical package.

Modifier 91: Repeat Lab Tests for Treatment Management

Modifier 91 is reserved for repeated clinical laboratory tests performed on the same day to monitor a patient’s condition or response to treatment. It differentiates these tests from mere repetitions due to errors or quality issues.

When to Use Modifier 91:

  • When the same lab test is repeated multiple times on the same day to track changes in a patient’s condition or treatment response.

When Not to Use Modifier 91:

  • When a test is repeated due to equipment failure or specimen inadequacy.

Quick Modifier Comparison

AspectModifier 59Modifier 25Modifier 91
PurposeDistinct procedural servicesSeparate identifiable E&M serviceRepeat lab tests for treatment management
ApplicationMultiple procedures in a single sessionAdditional E&M service on the same day as another serviceRepeated lab tests on the same day for follow-up
Billing ImpactPrevents under-billing or denialsEnsures proper billing for additional E&M serviceAccurate billing for repeated tests without implying errors
Common MisuseUsed to get a procedure paid without considering distinctnessAdded when there’s no significant E&M service beyond the primary procedureUsed for repeated tests due to initial errors


Are modifiers 25 and 59 interchangeable?

No, modifiers 25 and 59 have distinct purposes and coding mechanisms. Modifier 25 specifically addresses separate E&M services, while modifier 59 focuses on multiple distinct procedures.

What is the difference between modifiers 91 and 59?

Modifier 91 is used for repeated lab tests performed on the same day for treatment management, while modifier 59 is used for multiple distinct procedures performed during the same session.


Modifiers 59, 25, and 91 are crucial tools in medical billing, ensuring accurate coding, appropriate reimbursement, and streamlined financial processes. Understanding their nuances is essential for healthcare providers and billing professionals alike.

No Comments
Add Comment